Japanese scientists show that treating male mice with ergothioneine, a compound found in high concentrations in the lion's mane mushroom,
significantly extends median and average lifespan by 16% and 21%, respectively.
For the first time, researchers at Kanazawa University in Japan have demonstrated the longevity-supporting benefits of ergothioneine,
a powerful antioxidant and anti-inflammatory commonly found in lion's mane mushrooms.
Argotiona and previously received a lot of attention thanks to its ability to activate neuroprotection and increase physical performance in older mice.
But now, new data shows that ergothioneine also has longevity-enhancing properties,
when researchers demonstrated that ergothioneine significantly extends the lifespan of male mice.
These noteworthy findings open the door to further research on how ergothioneine can be applied in nutritional antiaging interventions.
A new study found ergothionine (ERGO), a powerful antioxidant found in lion's mane mushrooms, significantly extends the lifespan of male mice.
The research:
- This is the first study that comprehensively examines the effect of ERGO on life expectancy and age-related disorders.
- 7-week-old male mice were supplemented with ERGO in their drinking water for the rest of their lives.
- The dose of ERGO was about 4-5 mg/kg per day.
Results:
- The ERGO supplement significantly extended the lifespan of the mice.
- The median survival age increased by 16%.
- The average survival age increased by 21%.
- The threshold at which 90% of the mice reached mortality increased by 29%.
Similar findings were also observed in worms (c. elegans) that received ERGO.
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References:
https://pubmed.ncbi.nlm.nih.gov/38446314/
https://www.nmn.com/news/study-shows-lions-mane-mushroom-improves-memory-and-reduces-brain-inflammation
https://www.nad.com/news/lions-mane-restores-locomotor-performance
ERGO - ergothionine \ shelf ergothionine; (The links to IHERB include a 5% discount on the entire shopping basket - discount code KBZ701)
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