A team of scientists from Harvard Medical School discovered a combination of drugs that can reverse the aging process within a week!
The amazing findings were published in the July 2023 issue of the journal Aging and may lead to a revolution in the field of human health.
The study, published under the title "Possible Age Reversal Using Chemical Cocktails", was conducted on mice and included the administration of three different drugs:
The unique combination of these drugs resulted in an amazing regeneration of the aged muscles, liver tissue and other organs. In just one week, elderly mice returned to exhibit levels of physical activity and function similar to those of young mice.
The fascinating experiment:
The study, published under the title "Possible Age Reversal Using Chemical Cocktails", was conducted on mice in three main stages:
Step 1: Choosing the drugs:
- Growth hormone (GH): A well-known drug that promotes growth and tissue repair.
- Metformin: a common drug for the treatment of type 2 diabetes, with proven anti-aging effects.
- A drug that activates the enzyme AMPK: regulates metabolic processes and is important for the proper functioning of cells.
Step 2: Providing the treatment:
- Mice aged 18-24 months (equivalent to 60-80 in humans) received the drug combination for 7 days.
- A control group received a dummy drug (placebo).
Step 3: Analysis of the results:
- After 7 days, mice from both groups were tested in a variety of measures, including:
- physical activity
- muscle function
- Liver health
- vascular health
- Gene and protein levels related to aging
- The results of the analysis showed significant differences between the two groups:
- Mice that received the treatment demonstrated a significant improvement in physical activity, muscle function and liver health.
- The levels of genes and proteins associated with aging decreased significantly in the treatment group, and returned to levels similar to those of young mice.
- The control group did not show a significant change in these indices.
"We have previously shown that age reversal is possible through gene therapy," Sinclair tweeted.
"Now we show that it is possible with chemical cocktails, a step towards the regeneration of the whole body at a reasonable price."
Sinclair's team discovered that the combination of the drugs caused significant changes in the level of genes, proteins and metabolites in the cells of the mice.
These changes caused the cells to regenerate and become biologically younger.
References:
https://www.aging-us.com/article/204896/text
